Abstract: In the contemporary era, there has been a marked escalation in the frequency of malignant neoplasms, posing a substantial threat to the health and welfare of the human race. Despite the array of therapeutic modalities currently employed, cancer treatments have yet to reach a pinnacle of effectiveness. Standard interventions, including surgical resection, radiation treatment, and chemical therapeutics, although capable of curbing the proliferation of neoplastic cells, are frequently accompanied by considerable morbidity. The adoption of near-infrared photoimmunotherapy represents an innovative therapeutic paradigm, which selectively eliminates cancerous cells with heightened accuracy, minimal invasiveness, and straightforward application. The potential for this treatment approach to be merged with supplementary medicinal substances exists, enhancing its curative impact. An exhaustive examination of the latest progress in cancer therapy utilizing near-infrared light-based immunotherapy is delineated in this document, including research performed both in China and across the globe. This analysis aims to establish a comprehensive database, aiding in the practical utilization within the clinical sphere and bolstering the pursuit of additional scholarly exploration within the field. Read More

Abstract: Menopausal syndrome is a common clinical disease. In recent years, its incidence has shown a high growth rate and a younger trend, seriously threatening the physical and mental health of women. Acupuncture therapy starts from the whole body, regulates the functions of the zang-fu organs and Chong and Ren meridians, and can thus alleviate the clinical symptoms of patients. By retrieving relevant literature on acupuncture treatment of menopausal syndrome in recent years, this paper aims to explore the mechanism of acupuncture in treating this disease. Through analysis, it is found that acupuncture can intervene in the treatment of menopausal syndrome from multiple targets, multiple levels and multiple systems, mainly involving the neuro-endocrine system, immune system, vasomotor factors, monoamine neurotransmitters, oxidative stress levels and cell signaling pathways. By summarizing the relevant mechanisms of acupuncture in treating menopausal syndrome, this paper points out the existing deficiencies and development directions in current research, thereby deepening the understanding of acupuncture in treating menopausal syndrome and providing theoretical basis and new ideas for clinical practice. Read More

Abstract: Based on the monthly incidence data of AIDS, a SARIMA model and a SARIMA-SVM combination model are constructed to study and predict the number of cases, providing a scientific basis for the prevention and control of AIDS. The monthly incidence count data of AIDS from January 2004 to September 2023 are used as the training set, and the monthly incidence count data from October 2023 to September 2024 are used as the test set. Using R software, these two models are applied to predict the monthly incidence count of AIDS in China, and the predictions are compared with the actual values to evaluate the forecasting effectiveness of the single SARIMA model and the SARIMA-SVM hybrid model. The overall trend of AIDS incidence in China from 2004 to 2024 shows an upward trend, with certain seasonal characteristics. The root mean square error (RMSE) of the SARIMA model's forecast results is approximately 578.718, and the mean absolute percentage error (MAPE) is about 11.163%. The root mean square error (RMSE) of the SARIMA-SVM hybrid model's forecast results is approximately 45.643, and the mean absolute percentage error (MAPE) is about 0.838%. The SARIMA-SVM combination model has a good fit and prediction effect on the number of AIDS monthly incidence, and the prediction accuracy is high, which can be used to predict the month-by-month incidence data of AIDS. Read More

Abstract: In modern society, emotion regulation and cognitive flexibility play an important role in coping with daily stress. Stress, as a physiological and psychological reaction, may affect the individual's cognitive function and emotional regulation ability, and the flexibility of emotional regulation is closely related to the individual's psychological adaptability. This paper first reviews the concepts of stress, emotion regulation and cognitive flexibility. Secondly, the related theoretical models are introduced, especially the flexibility of emotion regulation and the cognitive control model. Finally, the interaction between stress, mental flexibility and depression was discussed, and the influence mechanism of different stress perception and emotion regulation strategies on depression was analyzed. Read More

Abstract: Background: The caring ability of nurses refers to their ability to care for, help, and take care of patients. Currently, due to the shortage of nursing human resources, nurses face high work pressure, and are generally lacking in emotional intelligence and self-regulation fatigue, which affects the nursing services they provide. Objective: The aim of this study is to identify the relevant factors associated with the nursing ability of nurses in the internal medicine and surgery wards of some hospitals in Shandong Province, clarify the relationship between nurses' emotional intelligence, self-regulation fatigue, stress, and caregiving ability, and provide reference for improving the quality of clinical nursing services. The sample size of this study is still relatively small, and the participants come from some hospitals in Shandong, which is a limitation and area for improvement in this study. Methods: A descriptive correlational study will involve 377 registered nurses who will be recruited via purposive non probability sampling. It will start in December 2024 and end within October 2025.The variables (emotional intelligence, self-regulatory fatigue, stress, and caring abilities) will be measured through research instruments, namely the Jefferson Nursing Student Physician-Patient Empathy Scale, Selective Caring Competency Scale, Walker and Avant's Conceptual Analysis Strategy, and Law's Emotional Discussion Scale. Descriptive statistics (mean, standard deviation, frequency, and percentage) and inferential statistics (Pearson r, Spearman rho) will be used for data analysis. Read More

Abstract: When vulnerable plaques in the coronary artery are ruptured or corrosive, they can easily lead to the occurrence of acute coronary syndrome (ACS). Today, various intracoronary imaging technologies can be used to detect vulnerable plaques. Traditional coronary CT angiography (CCTA, hereinafter referred to as coronary CTA) is considered a first-line choice for risk stratification of cardiovascular disease and to evaluate stable or unstable plaques. However, it mainly relies on subjective visual evaluation of diagnostic physicians and is prone to ignore many important features of vulnerable plaques. Imaging omics extracts many imaging features that cannot be captured by the human body from coronary CTA, which can better analyze and judge vulnerable plaques. This paper mainly reviews the application of imagingomics to evaluate the characteristics of vulnerable plaques in coronary CTA and related heart disease and other imaging techniques for vulnerable plaques and related clinical risk events. Read More

Abstract: As an important branch of artificial intelligence, machine learning algorithm has shown a wide range of application prospects and significant advantages in the optimization of personalized care programs. It can provide accurate diagnostic support, real-time health monitoring and personalized adjuvant treatment for patients by analyzing multi-source medical data, effectively improve the scientificity and accuracy of nursing programs, and alleviate the workload of nursing staff. We should improve the ability of nurses to understand and apply machine learning technology, to achieve more efficient, more accurate, and more personalized medical care services, and promote the innovation and development of medical care model. Read More

Abstract: Primary dysmenorrhea (PD) is a prevalent issue among young women, impacting academic performance due to frequent school absenteeism and reduced class concentration. This study focuses on college students in Shandong Province, China, aiming to determine PD prevalence, menstrual patterns, and associated risk factors. Cross-sectional study with a stratified sampling of 1297 participants from five universities. The cross-sectional approach will assess socio-demographic profiles, lifestyle habits, medical histories, and their correlation with academic outcomes. By identifying these factors, the study seeks to develop a targeted intervention framework to enhance pain management for affected students. Insights from this research are crucial for shaping effective strategies that address the multifaceted challenges posed by PD, ultimately aiming to mitigate its detrimental effects on educational attainment and student well-being. Read More