Abstract: Objective: To explore the implementation effect of the evidence-based practice plan for rehabilitation and nursing of cerebral stroke and swallowing disorders. Methods: 90 patients with cerebral stroke and dysphagia admitted to a hospital were selected and randomly divided into the experimental group and the control group, with 45 cases in each group. The experimental group implemented personalized nursing based on the evidence-based practice plan, including standardized diet management, swallowing function training and oral care; the control group adopted the traditional nursing model. Evaluate the nursing effect through the drinking water test, SWAL-QOL score and nursing satisfaction, and analyze the changes in the nursing quality of the two groups and the quality of life of patients. Results: The efficiency of nursing quality and swallowing function improvement of the experimental group (97.78%) was significantly higher than that of the control group (80.00%), the quality of life score and nursing satisfaction score are also significantly better than the control group (P<0.05). Conclusion: The evidence-based nursing plan for cerebral stroke swallowing disorder can significantly improve the nursing effect and effectively improve the patient's swallowing function and quality of life, which is worth promoting in clinical practice. Read More

Abstract: Diabetes Mellitus, a prevalent metabolic disorder, is increasingly acknowledged as a critical determinant of cognitive impairment. This comprehensive review synthesizes the current understanding of the pathophysiological mechanisms underlying cognitive deficits in diabetic individuals. It explores the contributions of chronic hyperglycemia, microvascular pathology, impaired insulin signaling, oxidative stress, and neuroinflammation as key drivers of neuronal injury and cognitive decline. And then the review delineates a range of risk factors—including advanced age, inadequate glycemic control, hypertension, and dyslipidemia—that exacerbate susceptibility to cognitive dysfunction in this patient population. The utility of advanced neuroimaging techniques and neuropsychological assessments in the detection and monitoring of cognitive changes is rigorously evaluated. Additionally, the article examines emerging preventive and therapeutic strategies, such as rigorous blood glucose control, management of cardiovascular risk factors, administration of antioxidants and anti-inflammatory agents, neuroprotective interventions, and psychological support. The review concludes with a discussion of its clinical relevance, underscoring the necessity for timely diagnosis and integrated management approaches to mitigate the cognitive burden of diabetes, and suggests avenues for future research aimed at addressing current knowledge voids and improving patient outcomes. Read More

Abstract: With the global aging trend, the elderly now bear a significant health economic burden. This study aims to explore effective compensation methods within a multi-tiered healthcare system for this group, focusing on China's aging society and medical security reform. Despite extensive research, gaps remain in elderly-specific compensation mechanisms. Utilizing health economics and a multi-level medical security framework, this study employs advanced techniques (e.g., machine learning) to assess elderly medical needs and costs, proposing scientific compensation strategies. Expected outcomes include reduced out-of-pocket costs, higher reimbursement rates, and broader insurance coverage, supporting policy formulation. The study also analyzes regional, economic impacts on elderly medical expenditures to ensure fair, efficient compensation. Read More

Abstract: Nowadays, the problem of sleep disorders is becoming more and more obvious around the world, which has attracted widespread attention. At present, the main solution to this problem is drug therapy, however, there are still many adverse effects of drug treatment, and some people have proposed that non-drug therapies such as music therapy can improve sleep quality. In this work, it will summarize how music therapy treats sleep disorders, reveal its internal mechanism, and this article also compares the differences between Chinese and Western music therapy interventions for sleep disorders. Finally, it looks forward to future research to look for shortcomings. Read More

Abstract: Tumors, due to their complex pathophysiological properties and potential drug resistance, make it difficult for traditional treatment modalities, including radiotherapy, chemotherapy and immunotherapy, to completely eliminate tumor cells. As an emerging therapeutic strategy, bacteriotherapy demonstrates its unique advantages, which are highly targeted. Whether applied alone or in combination with nanotechnology, bacterial therapy can effectively prevent tumor recurrence and metastasis. With the help of genetic engineering technology, it is possible to enable bacteria to express anti-cancer drugs, and these bacteria are able to precisely target the tumor area and release therapeutic molecules to induce apoptosis of tumor cells. Bacteria-targeted therapy has great potential for development in the field of tumor therapy. The paper reviews the research progress of bacterial therapies, introduces the principle of various bacterial therapies for tumor treatment, the research progress of bacterial therapies combined with nanotechnology, and the limitations of this therapy. Read More

Abstract: With the accelerated aging process in China, there are more and more diabetic patients, especially the elderly. The function of pancreatic β-cells in the elderly body gradually declines, insulin secretion ability decreases, and blood glucose regulation ability is weakened. In addition, the body's tolerance to glucose decreases, easily triggering diabetes. The high prevalence of diabetes mellitus and the high number of risk factors make it easy to cause various complications. Based on this situation, in recent years, the research on the treatment and care of diabetic patients has also made good progress, basically favoring nutritional intervention, which is more effective and less likely to induce adverse reactions, and is a more popular intervention. Therefore, this paper will synthesize the research results of scholars at home and abroad, discuss and analyze the research progress of nutritional intervention in diabetes mellitus patients, and provide certain references and reference for the dietary care of diabetes mellitus patients in the future. Read More

Abstract: Lumbar intervertebral disc herniation is a common disease in orthopedics, which seriously affects the quality of life of patients. This paper summarizes the therapeutic principles and clinical applications of these three therapies by comprehensively analyzing the literature related to acupuncture, moxibustion and tuina in Chinese medicine in recent years, with the aim of providing clinicians with new therapeutic perspectives and optimizing the existing treatment protocols, with a view to providing patients with more efficient and high-quality treatments. Read More

Abstract: Up to 80% of children with autism spectrum disorders (ASD) experience sleep disorders, which can manifest in five predominant forms. Although the causes of sleep disorders in these children remain unclear, the relationship between autism—considered a neurodevelopmental disorder—and the critical role of sleep in neurodevelopment has prompted significant interest among researchers and clinicians. Over the past decade, numerous trials have explored both non-pharmacological and pharmacological interventions to improve sleep in children with autism. A review of numerous randomized controlled trials on sleep in children with autism has shown that, while no definitive conclusions have been reached regarding the most effective intervention, melatonin appears to be the most promising option based on its widespread use in studies. Recent experimental evidence also addresses concerns from earlier research about the long-term efficacy and safety of melatonin. However, further exploration is needed to determine the most effective doses of melatonin for different severities of sleep disorders. Read More

Abstract: In recent years, adolescent depression has become a significant public health issue globally, profoundly affecting the quality of life, academic performance, and social functioning of adolescents. According to the China National Mental Health Development Report (2019-2020) released by the Institute of Psychology, Chinese Academy of Sciences in 2021, the detection rate of depression among Chinese adolescents is 24.6%, with severe depression accounting for 7.4%. Against this backdrop, the author has decided to conduct a comprehensive analysis of adolescent depression. This review aims to summarize the current state of research on adolescent depression to assist future researchers in better understanding and addressing this issue, thereby reducing the rate of adolescent depression. The methodology involved literature searches using "adolescent depression" as the keyword on CNKI, yielding 449 articles. After categorization and exclusion, the author found that current research on adolescent depression includes its definition, epidemiological data, causes and risk factors, impacts, diagnostic methods, treatment and intervention measures, and prevention strategies. This paper focuses on discussing the influencing factors and the evolution of treatment methods for adolescent depression and concludes with preliminary suggestions for future research. Read More

Abstract: Memory is a core problem in cognitive psychology and is crucial to understanding the acquisition, preservation and extraction of information. This study summarizes the dynamics of memory mechanisms, including theoretical evolution, systematic partitioning, process analysis, performance factors, barrier exploration, and clinical practice. Starting with the basic concept of memory and its importance in psychology, this paper reviews the background and value of memory research, and makes an in-depth study of classical and modern memory models to deepen the understanding of memory operation. Types of memories, such as instantaneous, persistent, unconscious, and conscious, are distinguished, with emphasis on encoding, retention, extraction, and fading. This paper discusses the biological, psychological, sociocultural, and environmental factors that influence memory, and highlights advances in the study of memory disorders, interdisciplinary collaboration, and neuroimaging. It concludes with a summary of the findings and future directions, including personalized memory enhancement and contributions to education, healthcare, and social development. This study deepens the understanding of memory mechanism and has practical guiding significance. Read More

Abstract: This study examines the challenges and prospects of mental health services in disaster-prone areas of the Philippines. Natural disasters frequently result in significant psychological impacts on survivors, including anxiety, depression, and post-traumatic stress disorder (PTSD). However, existing mental health services remain inadequate due to cultural stigma, a shortage of trained professionals, and limited resources. To address these gaps, the study proposes strengthening community-based mental health capacities, implementing public education campaigns to combat stigma, and incorporating mental health initiatives into disaster recovery frameworks. These measures are essential for improving disaster recovery outcomes and fostering long-term community resilience. Read More

Abstract: Objective: To investigate the status quo of dietary nutrition knowledge, belief and behaviors of patients with colorectal cancer undergoing radiotherapy, and to analyze its influencing factors, so as to provide basis for clinical nutrition management. Methods: a convenient sampling method was used to select 200 patients with colorectal cancer who received radiotherapy in the oncology department of three Grade A hospitals in Binzhou City from January to May 2024 for related study. A questionnaire survey was conducted on the knowledge, belief and behavior of total nutrition management of the respondents. In addition, demographic and clinical factors that may affect KABP in hospitalized patients with radiotherapy were investigated and analyzed, so as to provide a basis for formulating nutritional management measures for hospitalized patients with colorectal cancer with radiotherapy in clinical work. Results: The results showed that the average score of nutritional knowledge was 5.03±4.04, and the passing rate was 24.53%. The average score of nutrition attitude was 27.78±5.90, the pass rate was 80.19%; The average score of nutrition behavior was 29.05±8.86, and the pass rate was 18.4%. Age, sex, family residence, education level, occupation, family monthly income, type of medical insurance, type of radiotherapy and whether or not concurrent chemotherapy had significant differences in the total score of dietary nutrition knowledge and practice of patients with colorectal cancer inpatient radiotherapy. Discussion: This study showed that inpatients with radiotherapy for colorectal cancer had insufficient dietary nutrition knowledge reserve and poor nutritional behavior, but positive attitude towards nutrition. Gender, family per capita monthly income, family location and treatment were the main factors affecting the knowledge and practice of dietary nutrition in patients with colorectal cancer radiotherapy, especially the family residence, which had the greatest influence. Read More

Abstract: As a non-invasive and dynamic blood volume monitoring technology, the application value of PVI (Peripheral Vascular Index) in cesarean section for preeclampsia patients has received attention. This study adopted a prospective randomized controlled trial, enrolling 120 preeclampsia patients who underwent cesarean section, and were randomly assigned to receive either PVI-guided volume management or traditional volume management. The results showed that PVI-guided volume management effectively reduced the incidence of intraoperative hypotension, decreased fluid intake, and increased urine output. Additionally, it improved the Apgar score and umbilical artery blood pH value of newborns, optimizing maternal and fetal outcomes. PVI allowed for real-time assessment of blood volume changes, making volume management more precise and enhancing perioperative hemodynamic stability. The study results indicate that PVI has high clinical application value in anesthesia management for preeclampsia patients. Future large-scale, multi-center studies are needed to optimize perioperative volume management strategies, improve surgical safety, and enhance prognosis quality. Read More

Abstract: In addressing the limitations of conventional experience-based speed allocation in competitive swimming, the objective of this study is to develop optimal strategies from a biomechanical and metabolic perspective, leveraging advanced tools such as mathematical modeling. Specifically, the forces on swimmers during freestyle at different stages were analyzed, and energy consumption was assessed with the ATP-CP model. The analysis included energy expenditure, speed limits, and collision losses. Subsequently, an optimization model for speed allocation was developed using the Euler-Lagrange method and Particle Swarm Optimization (PSO). The results show that in the 50-meter race, swimmers achieve a 0.3-second improvement when they rapidly attain and maintain their maximum sprint speed. For the 100-meter event, the initiation of a rapid increase in speed during the first half, followed by the maintenance of a steady pace, results in a 0.7-second enhancement. In the 200-meter race, a more uniform distribution of speed, coupled with a slight acceleration towards the finish line, results in a performance enhancement of 1.2 seconds. Furthermore, numerical simulations demonstrate that optimal strategies can reduce average power consumption by approximately 15% in comparison to conventional methods. These findings provide scientific support for the effectiveness of optimized speed distribution in improving athlete performance. Read More

Abstract: To ensure the safe production of Jianqu, the dominant strains —Absidia corymbifera, Lichtheimia ramosa, and Mucor circinelloides—identified through high-throughput sequencing analysis, were inoculated onto sterile Jianqu-building substrates for cultivation. Their appearance characteristics were observed, and the liquefying and saccharifying power of their amylase were measured. Subsequently, Saccharomycopsis fibuligera, Millerozyma farinose, Hyphopichia burtonii, Absidia corymbifera, Lichtheimia ramosa, Mucor circinelloides, and Monascus purpureus were co-inoculated onto Jianqu-building substrates in different proportions for composite fermentation. The fermentation phenomena were observed, and the liquefying and saccharifying power of amylase were detected to further evaluate the effects of restricted composite fermentation using different proportions of dominant strains. The results showed that when the ratio of yeast (Saccharomycopsis fibuligera, Millerozyma farinose, Hyphopichia burtonii were mixed in a ratio of 2: 1: 1): Absidia corymbifera :Lichtheimia ramosa :Mucor circinelloides :Monascus purpureus was 2:4:3:2:1, the fermentation product achieved the ideal state of "ubiquitous white mold with a fragrant alcoholic aroma." The changes in amylase liquefying and saccharifying power exhibited an "S"-shaped curve. At 84 hours of fermentation, the liquefying power reached 2.11 ± 0.08U, and the saccharifying power reached 398 ± 5U, significantly outperforming natural fermentation (P < 0.05). Conclusion: By adjusting the inoculation ratios of dominant strains, the liquefying and saccharifying power of amylase can be significantly enhanced, thereby shortening fermentation time and improving the quality of Jianqu fermentation. Read More