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Advances in Indocyanine Green Fluorescence Imaging for Laparoscopic Hepatectomy

Hongzheng Li, Tengmeng Zhong
Vol.6, No.7, pp.82-90, 2026 DOI: 10.62051/ijphmr.v6n7.12 August 28, 2026
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Abstract: Indocyanine green (ICG) near-infrared fluorescence imaging enables real-time, repeatable, and radiation-free navigation during laparoscopic hepatectomy. Its applications have expanded from tumor localization to segmental staining, delineation of anatomical resection planes, margin assessment, biliary visualization, and evaluation of parenchymal perfusion. Current evidence indicates that ICG-guided surgery is associated with improved detection of small or superficial lesions, higher R0 resection rates, and improvements in selected perioperative outcomes. Nevertheless, performance is affected by liver function, dose and timing, lesion depth, staining strategy, and imaging-system characteristics. Evidence from robust randomized trials and long-term oncological follow-up remains limited. This narrative review summarizes the principles, clinical applications, evidence, limitations, and future directions of ICG fluorescence imaging in laparoscopic hepatectomy, with emphasis on Chinese- and English-language literature published from 2021 to 2025.
Keywords: Indocyanine green, Near-infrared fluorescence, Laparoscopic hepatectomy, Anatomical liver resection, Liver neoplasm, Precision surgery
APA Citation: Hongzheng Li, Tengmeng Zhong (2026). Advances in Indocyanine Green Fluorescence Imaging for Laparoscopic Hepatectomy. International Journal of Public Health and Medical Research, 6(7), 82-90. https://doi.org/10.62051/ijphmr.v6n7.12

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